San Marco
The sestiere around the basilica and the piazza is the postcard and carries the prices to match. Staying here puts the major sights on your doorstep and places you inside the densest day-visitor flow between roughly mid-morning and late afternoon. Early mornings and evenings are the reward, which is the honest case for paying for it.
The basilica, the piazza and being at the centre.
The highest prices and the densest day-visitor crowds.